This work assesses the potential of Sentinel-2A images in precision agriculture for Barley production in a case study. Two workflows are proposed: 1) images were acquired with a relatively simple methodology to follow the crop development; 2) two images around harvest time were downloaded and processed using a more complex and accurate methodology to calculate four vegetation indices (NDVI, WDRVI, GRVI and GNDVI) to be correlated to yield with linear regression models.